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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Adv Biosyst. 2020 Sep 13;4(11):e2000129. doi: 10.1002/adbi.202000129

Figure 2.

Figure 2.

Effect of (A) 3-day or (B) sustained ROCK inhibition on YAP nuclear localization and iPSC aggregate morphology on day 7 post-encapsulation. (C) Distribution of aggregate diameters of the aggregates for 3-day and sustained Y-27632 treatment. The diameters of the aggregates for 3-day and sustained treatment conditions were 78.7 ± 3.0 μm (N = 72) and 90.3 ± 5.93 μm (N = 48) respectively. Aggregate diameters were quantified using live/dead staining images at day 7 post-encapsulation with ImageJ software. The diameters were analyzed using a Kolmogorov-Smirnov test of the cumulative frequency distributions (p = 0.67).