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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Heart Lung Transplant. 2020 Sep 28;39(12):1476–1490. doi: 10.1016/j.healun.2020.09.012

Figure 1.

Figure 1.

Identification of miRNAs involved in lung IR injury. A. Increased expression of miR-206 in BAL fluid of patients on day 1 post-lung transplantation compared to day 0 was observed. n=4-5/group; *p=0.007. B. Total RNA obtained from lung tissue of WT mice from the hilar ligation model of IR injury was analyzed by miRNA microarray. Hierarchical cluster analysis of lung IR injury compared to sham is shown by heat map for the highly regulated miRNAs. Each column represents the respective sample, and each row represents a single miR probe. C. The most significant increase was observed in miR-206 expression in the lung tissue after IR compared to sham. n=5/group; #p=0.006.