Table 3.
Clinical correlations by group.
| BD | SAD | SZ | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BACS | BGErr | SGErr | SErr | BACS | BGErr | SGErr | SErr | BACS | BGErr | SGErr | SErr | |
| Current Symptoms | ||||||||||||
| PANSS Positive | −.10 | .16 | .12 | .12 | −.11 | .07 | .14 | .20 | −.13 | .12 | <.01 | .11 |
| PANSS Negative | −.38* | .23 | .18 | .25* | −.24* | .17 | .18 | .17 | −.20 | .13 | .26* | .13 |
| MADRS Total | −.13 | .09 | .04 | .08 | −.15 | .18 | .01 | .09 | .03 | <.01 | −.01 | .01 |
| YMRS Total | .01 | .02 | .05 | −.03 | .03 | −.07 | −.04 | .03 | −.12 | .03 | −.13 | .01 |
| Medication | ||||||||||||
| CPZ Dose | −.16 | .15 | .12 | .07 | −.05 | .04 | .15 | <.01 | −.06 | −.03 | .05 | −.06 |
| Lithium Dose | −.03 | −.01 | .15 | .02 | .01 | −.09 | .04 | <.01 | .02 | .09 | .03 | .02 |
| Valproic Acid Dose | <.01 | .03 | .04 | −.07 | .06 | −.02 | .05 | .05 | −.05 | −.01 | .01 | −.02 |
| Sedative Use | <.01 | −.05 | −.03 | .12 | −.13 | .09 | .12 | .08 | <.01 | −.02 | .06 | −.03 |
| Impulsivity | ||||||||||||
| BIS | −.05 | <.01 | −.06 | −.05 | −.16 | .10 | .02 | .08 | −.14 | .05 | −.03 | .14 |
| Total | ||||||||||||
| BIS Attentional | .07 | −.01 | −.06 | −.05 | −.07 | .08 | −.02 | .02 | −.09 | .04 | −.02 | .13 |
| BIS Motor | −.02 | −.03 | −.10 | −.05 | −.06 | .01 | .03 | .08 | −.08 | −.01 | <.01 | .08 |
| BIS Non-planning | −.14 | .05 | .01 | −.04 | −.19 | .13 | .02 | .08 | −.10 | .07 | −.03 | .14 |
| Suicide | ||||||||||||
| History of suicide | .03 | −.02 | −.05 | −.01 | .08 | .03 | −.06 | .08 | .09 | −.08 | .04 | <.01 |
| Suicide severity | .03 | −.01 | −.05 | .01 | .06 | .08 | <.01 | .11 | .07 | −.06 | .02 | .08 |
| Suicide count | .02 | −.03 | −.06 | −.06 | −.02 | .06 | −.10 | .08 | .14 | −.10 | −.04 | −.08 |
| BD | SAD | SZ | ||||||||||
| BGRT | SGRT | AS | SSRT | BGRT | SGRT | AS | SSRT | BGRT | SGRT | AS | SSRT | |
| Current Symptoms | ||||||||||||
| PANSS Positive | .03 | <.01 | −.04 | .10 | −.15 | −.02 | −.18 | .16 | .06 | −.06 | −.12 | −.02 |
| PANSS Negative | .19 | −.03 | −.25* | .22 | .14 | .06 | −.12 | .20 | .28* | .08 | −.28* | .14 |
| MADRS Total | .01 | −.09 | −.10 | −.01 | .05 | −.07 | −.11 | −.02 | .07 | −.05 | −.12 | −.09 |
| YMRS Total | .04 | .03 | −.02 | −.02 | −.06 | −.11 | −.03 | −.03 | −.05 | −.17 | −.09 | −.15 |
| Medication | ||||||||||||
| CPZ Dose | .11 | .02 | −.11 | .12 | .13 | .08 | −.09 | .03 | .05 | .10 | .02 | −.02 |
| Lithium Dose | .06 | .10 | .02 | .13 | −.06 | −.03 | .06 | −.04 | <.01 | <.01 | <.01 | .05 |
| Valproic Acid Dose | −.01 | .09 | .10 | −.01 | <.01 | .01 | .01 | .07 | .03 | .06 | .01 | .08 |
| Sedative Use | −.10 | −.10 | −.02 | −.08 | .07 | −.04 | −.14 | .02 | .03 | .05 | <.01 | .03 |
| Impulsivity | ||||||||||||
| BIS Total | −.13 | −.08 | .08 | −.13 | .04 | −.05 | −.08 | .10 | <.01 | −.14 | −.11 | −.02 |
| BIS Attentional | −.14 | −.10 | .07 | −.16 | .02 | .01 | −.02 | .13 | .02 | −.09 | −.10 | .04 |
| BIS Motor | −.17 | −.09 | .11 | −.15 | −.01 | −.08 | −.05 | −.02 | .07 | −.08 | −.15 | <.01 |
| BIS Non-planning | −.04 | −.02 | .02 | −.05 | .07 | −.04 | −.11 | .12 | −.10 | −.15 | −.02 | −.04 |
| Suicide | ||||||||||||
| History of suicide | .01 | −.06 | −.07 | <.01 | .04 | −.05 | −.09 | .01 | .03 | .05 | <.01 | .06 |
| Suicide severity | −.03 | −.08 | −.04 | .01 | −.01 | −.12 | −.09 | .01 | .02 | .06 | .03 | .04 |
| Suicide count | <.01 | .01 | <.01 | −.05 | .06 | −.05 | −.12 | −.01 | −.01 | −.03 | −.01 | −.03 |
BACS = Brief Assessment of Cognition in Schizophrenia; PANSS = Positive and Negative Symptom Scale; MADRS = Montgomery-Asberg Depression Rating Scale; YMRS = Young Mania Rating Scale; CPZ = Chlorpromazine equivalent antipsychotic dose; BIS = Barratt Impulsiveness Scale; BGErr = Baseline Go errors; SGErr = SST Go errors; SErr = Stop errors; BGRT = Baseline Go reaction time; SGRT = SST Go reaction time; AS = adaptive slowing; SSRT = Stop Signal Reaction Time.
*
FDR corrected p-value.