The content of global methylated DNA (5-mC) in the blood and pancreas of control (ctrl), diabetic (Dia) and OF (20 mg/ml)- treated rats. After 8 weeks treatment, DNA was extracted from the blood and pancreas of rats and DNA methylation status was measured using MethylFlash™ global DNA methylation (5-mc) ELISA easy kit. Control, ctrl; diabetic, Dia; and OF, Oligosaccharide fraction. The results are the mean ± SD of triplicate experiment (P < 0.05). *, significantly different from control group