Skip to main content
. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Mol Neurobiol. 2020 Sep 9;58(1):143–155. doi: 10.1007/s12035-020-02107-w

Figure 6. Impaired learning occurs later than mitochondrial defects, cell death and plaque formation.

Figure 6.

Performance Index (PI) when tested at 3 min after olfactory and negatively reinforced, classical conditioning. The PI ranges from zero to 1.0, where zero represents no memory observed and 1.0 represents complete memory. Flies carrying only the R13-Gal4 driver transgene (+/ +; R13F02-Gal4/ +) or the UAS-Aβ42 transgene (+/ UAS-Aβ42; +/ UAS-Aβ42) were used as controls for the experimental group carrying both transgenes (+/ UAS-Aβ42; R13F02-Gal4/UAS-Aβ42). Flies were trained and tested at 1, 5, 10, and 15 days-of-age. No significant differences between the controls and the experimental groups were observed at any age except at 15 days-of-age. One-way ANOVA followed by Tukey’s multiple comparison, **P<0.01, ***P<0.001. n=8. Box plots show the median, interquartile range, and the range.