Table 2.

Top 20 hub proteins based on degree score

No	Protein symbol	Protein name	Degree score
1	APP	Amyloid-beta A4 protein	56
2	ADCY8	Adenylate cyclase type 8	53
3	ADCY2	Adenylate cyclase type 2	51
4	ADCY5	Adenylate cyclase type 5	48
5	ADCY9	Adenylate cyclase type 9	48
6	ADCY6	Adenylate cyclase type 6	48
7	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	45
8	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3	42
9	AGT	Angiotensinogen	40
10	ADRB2	Beta-2 adrenergic receptor	40
11	EDN1	Endothelin-1	39
12	GNG2	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	39
13	IL6	Interleukin-6	38
14	CXCL8	Interleukin-8	38
15	POMC	Pro-opiomelanocortin	37
16	MAPK1	Mitogen-activated protein kinase 1	37
17	AVP	Vasopressin-neurophysin 2-copeptin	37
18	INS	Insulin	36
19	MMP9	Matrix metalloproteinase-9	35
20	GCG	Glucagon	35