Table 1.

An Overview of the 8 Transcriptional Profiling Studies Included in Our Current Meta-analysis of Differential Gene Expression in the bHR and bLR Hippocampus at 4 Developmental Time Points: P7, P14, P21, and Adulthood

	MBNI_AffymetrixRae230_F4	MBNI_AffymetrixRgU34A_F6	MBNI_AffymetrixRae230_F15	MBNI_IlluminaRatRef12v1_F15	MBNI_RNASeq_F29	Alabama_Nimblegen_F34	MBNI_RNASeq_F37	MBNI_RNASeq_F43
Generation	4	6	15	15	29	34	37	43
Laboratory	MBNI	MBNI	MBNI	MBNI	MBNI	Alabama	MBNI	MBNI
Lead Scientist	Dr. John Stead	Dr. Sarah Clinton	Dr. Sarah Clinton	Dr. Sarah Clinton	Dr. Sarah Clinton	Dr. Sarah Clinton	Dr. Peter Blandino	Dr. Cigdem Aydin
Age	Adult	P7, P14, P21	P14	P14	P14, adult	P7, P14, P21, adult	Adult	Adult
n per Group	6	6	6	6	2	5	6	5
Platform	Affymetrix Rat Expression Set 230 A	Affymetrix Rat Genome U34A GeneChips	Affymetrix Rat Expression Set 230 A	Illumina RatRef-12 v1 BeadChip	RNA-Seq	NimbleGen Rat Gene Expression 12x135	RNA-Seq	RNA-Seq
Tissue Extraction	Whole hippocampus	Whole hippocampus	Whole hippocampus	Whole hippocampus	Whole hippocampus	Dorsal hippocampus tissue punch	Whole hippocampus	Whole hippocampus
Treatment	Basal	Basal	Basal	Basal	Basal	Basal	Basal	Vehicle injections
Behavioral Testing	Basal	Basal	Basal	Basal	Basal	Basal	Locomotor, anxiety	Social interaction after mild stress
GEO Data Release	GSE140596	GSE29552	GSE140595	GSE140594	GSE140597	GSE88874	GSE140598	GSE140287
Citation		Clinton et al. (14)				Cohen et al. (28)

See (14,28). Note that the MBNI_RNASeq_F37 dataset was collected from a subset of bHR and bLR rats included in the exome sequencing study (25).

bHR, bred high-responder; bLR, bred low-responder; GEO, Gene Expression Omnibus; MBNI, Molecular Behavioral Neuroscience Institute; P, postnatal day; RNA-Seq, RNA sequencing.