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. Author manuscript; available in PMC: 2021 May 23.
Published in final edited form as: Nat Methods. 2020 Nov 23;17(12):1191–1199. doi: 10.1038/s41592-020-01000-7

Extended Data Fig. 9. X-chromosome inactivation promoter comparisons.

Extended Data Fig. 9

Methylation and accessibility in 500 bp and 100 bp windows, respectively, centered at TSS compared between maternal and paternal alleles (N = number of genes in the group), (a) by plotting and comparing the distributions using boxplots and one-sided Wilcoxon rank-sum test (Data are presented as median values, interquartile range (IQR), and 1.5X IQR, CpG XCI Pat > Mat p-value = 0, GpC XCI Mat > Pat p-value = 1.9e-229 ), and (b) by density plots of the difference in methylation frequencies between the two alleles.