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. Author manuscript; available in PMC: 2021 May 23.
Published in final edited form as: Nat Methods. 2020 Nov 23;17(12):1191–1199. doi: 10.1038/s41592-020-01000-7

Figure 5. Comparative epigenomic analysis of breast cancer model.

Figure 5.

Read-level methylation and accessibility plots (a) near an insertion that is present in MCF-7 and MDA-MB-231 but not in MCF-10A, showing changes in methylation and accessibility downstream of the insertion, and (b) on the TSS of ZNF714 gene, which is upregulated in MCF-7 and MDA-MB-231 in comparison to MCF-10A, showing the differences in the estimated protein binding and combinatorial epigenetic signatures.