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. Author manuscript; available in PMC: 2021 May 23.
Published in final edited form as: Nat Methods. 2020 Nov 23;17(12):1191–1199. doi: 10.1038/s41592-020-01000-7

Extended Data Fig. 4. GpC accessibility kernel estimation on single reads.

Extended Data Fig. 4

GpC methylation calls were smoothed using a Gaussian kernel estimator. (a) Distributions of length of accessible and inaccessible runs and (b) metaplot of accessibility near CTCF binding sites before and after the smoothing, along with (c) example of read-level plot of accessibility from a 2kb region around a CTCF binding site.