Table 2.
Phosphorylated MmpL3, MmpL11, and MmpL7 residues identified in H37Rv
| MmpL3 Peptide (#, identified residue) | AA | Differentially phosphorylated in stationary phaseb |
|---|---|---|
| AAGDPRPPHDPT#HPLAESPRPAR b, e | T789 | |
| SSPASSPELTPALEATAAPAAPS#GASTTR b | S823 | |
| MQIGSST#EPPTTR b | T836 | yes |
| MQIGSSTEPPT#TR a, e | T840 | |
| SVQSPAS#TPPPTPTPPSAPSAGQTR e | S855 | |
| SVQSPAST#PPPTPTPPSAPSAGQTR b | T856 | yes |
| SVQSPASTPPPT#PTPPSAPSAGQTR a | T860 | |
| SVQSPASTPPPTPT#PPSAPSAGQTR b | T862 | yes |
| SVQSPASTPPPTPTPPS#APSAGQTR e | S865 | |
| SVQSPASTPPPTPTPPSAPS#AGQTR e | S868 | |
| SVQSPASTPPPTPTPPSAPSAGQT#R a, e | T872 | |
| SVQSPASTPPPTPTPPS#APSAGQTR b | S865 | yes |
| STDAAGDPAEPT#AALPIIR a, b, e | T893 | yes |
| STDAAGDPAEPT#AALPIIRS#DGDDSEAATEQLNAR b, f | T893, S901 | |
| STDAAGDPAEPT#AALPIIRSDGDDSEAAT#EQLNAR b | T893, T910 | |
| SDGDDS#EAATQLNAR b | S906 | yes |
| SDGDDSEAAT#EQLNAR a, b, e, f | T910 | yes |
| MmpL7 Peptide | Start AA | |
| KVESAAWPAGVPWTDASLSSAAGRLADQLGQQAGc | 467 | |
| ISAISTQTMSALSSAPRMVAQMR c | 611 | |
| HVRESMFSSDGTATR c | 693 | |
| MmpL11 Peptide | AA | |
| VAGAAQVDVGGPT#ALIKDFDDR d | T514 | |
| LAPDAICVTDPLAFT#GCGCDGKALDQVQLAYR a, d | T765 | |
| RLAVALDALQT#TTWECGGVQTHR d | T821 | |
| LAVALDALQT#T#TWECGGVQTHR d | T821, T823 | |
| RCLS#VAVAMLEEAR d | S956 |
a.
Prisic et al, 2010. Only unambiguous residues shown.
b.
Verma et al., 2017. Only unambiguous residues shown.
c.
Perez et al, 2006. This study did not identify exact residue phosphorylated.
d.
Melly et al., 2020.