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. Author manuscript; available in PMC: 2021 Nov 20.
Published in final edited form as: Free Radic Biol Med. 2020 Jul 30;160:630–642. doi: 10.1016/j.freeradbiomed.2020.07.032

Fig. 11: Apoptotic effects of IR, GC4419, and combination in lung cancer and normal immortalized cells.

Fig. 11:

Lung cancer cells A549 and H1299 or normal immortalized cells Beas 2b were either left untreated or treated with 2 Gy (IR), 10 μM GC4419 (GC;), or combination then maintained for 48 hr in a humidified atmosphere of 95% air: 5% CO2 at 37 0C . Cells were washed, trypsinized, and DNA fragmentation (A) and Caspase-3 activity (B) were performed. Results are presented as mean ± SEM of three independent experiments. *significant from control (p < 0.05), ** significant from control (p<0.001), # significant from IR (p<0.001).