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. Author manuscript; available in PMC: 2021 Mar 10.
Published in final edited form as: Nature. 2020 Sep 10;587(7835):673–677. doi: 10.1038/s41586-020-2749-z

Extended data Figure 8. Mutations at the cGAS-nucleosome interface affect nucleosome binding by human cGAS.

Extended data Figure 8.

a. SDS-PAGE analysis of biotin-labeled full-length human cGAS mutants used for the SPR binding studies.

b - n. SPR binding studies of full-length human cGAS mutants with reconstituted nucleosomes.