. 2020 Sep 12;99(12):6493–6502. doi: 10.1016/j.psj.2020.09.012

Table 4.

Hematological and clinical chemistry outcomes of birds receiving the dried egg product containing anti–IL-10 antibody via feed during a challenge infection with Eimeria.¹

Item	Outcome	Treatment				Pooled SEM	Model, P-value
Item	Outcome	UCON	ICON	I-143 or I-165	I-287	Pooled SEM	Model, P-value
Study 1
DPI 5	Heterophils, %	29.27^b	18.93^c	38.67^a	16.73^c	3.053	<0.001
	Monocytes, %	2.60^b	6.93^a	7.86^a	3.80^b	0.868	0.001
	Lymphocytes, %	64.73^a	71.20^a	46.80^b	76.46^a	3.426	<0.001
	Basophils, %	2.93^b	2.40^b	5.20^a	2.53^b	0.624	0.007
	Total protein, g/dL	2.83^a	2.56^b	2.52^b	2.57^b	0.044	<0.001
	Glucose, mg/dL	300.27^b	355.21^b	404.87^a	376.13^a	20.210	0.004
	Calcium, mg/dL	8.88^a	8.52^a	7.31^b	7.71^a	0.338	<0.001
DPI 7	Hematocrit, %	30.80^a	28.87^a,b	28.27^b	28.07^b	0.609	0.009
	Monocytes, %	3.13^b	6.53^b	7.47^a	7.47^a	0.980	0.007
	Basophils, %	3.07^b	4.73^b	6.07^a	5.20^a,b	0.717	0.030
	Eosinophils, %	1.13^a,b	1.47^a	0.27^c	0.40^b,c	0.276	0.007
Study 2
DPI 5	Hematocrit, %	25.63^a	16.00^b	14.86^b	18.71^a,b	2.631	0.005
	Total protein, g/dL	2.85^a	2.67^a,b	2.53^b	2.54^a,b	0.106	0.023
	Basophils, %	4.53^a	2.40^a	1.50^b	1.71^a,b	0.879	0.005
	Albumin, g/dL	0.94^b	1.39^a	1.29^a	1.34^a	0.063	<0.001
	Glucose, mg/dL	316.53^b	312.07^b	275.46^b	392.33^a	21.107	0.001
DPI 7	Hematocrit, %	25.73^a,b	28.00^a	26.86^a,b	24.83^b	0.749	0.009
	Monocytes, %	1.67^b	5.93^a	5.85^a	8.00^a	1.095	0.007

^a–cMeans lacking a common superscript letter within a row differ (P < 0.05).

Abbreviations: DEP, dried egg product; DPI, d post infection; I-143, infected birds receiving 143 U/tonne of DEP; I-165, infected birds receiving 165 U/tonne of DEP; I-287, infected birds receiving 287 U/tonne of DEP; ICON, infected control; UCON, uninfected control.

Only significant results are shown. The dried egg product was supplemented at a dose of 143 or 287 (study 1) and 165 or 287 U/tonne (study 2). All birds in the infected groups received an oral inoculum containing either 200,000 E. acervulina (study 1) or 80,000 E. tenella (study 2) sporulated oocysts at study day 12. Least square means derived from samples derived from 1 bird in each of the 15 replicate battery cages (n = 15) at each independent collection time point.