Table 5.
Summary of histopathological lesion scores of individual birds receiving the dried egg product via feed during a challenge infection with either E. acervulina (study 1) or E. tenella (study 2) at day 12.1
Item | Treatment |
Pooled SEM | Model, P-value | ||
---|---|---|---|---|---|
ICON | I-143 or I-165 | I-287 | |||
Study 1 | |||||
Villous atrophy | 2.14b | 2.25a | 2.50a | 0.093 | 0.025 |
Heterophils | 1.44a | 1.82a | 0.82b | 0.174 | 0.009 |
Bacterial dysbiosis | 1.61a | 1.68a | 0.93b | 0.162 | 0.004 |
Enteritis score | 16.24a,b | 16.75a | 15.00b | 0.474 | 0.036 |
Study 2 | |||||
Lymphoid hyperplasia | 2.60b | 2.51b | 3.18a | 0.182 | 0.014 |
Fibroblast hyperplasia | 3.20b | 4.05a | 4.35a | 0.225 | 0.003 |
Cystic crypts | 1.00b | 2.29a | 2.44a | 0.243 | 0.002 |
Enteritis score | 12.87b | 15.29a,b | 17.38a | 0.967 | 0.005 |
Total lesion score | 17.87b | 20.29a,b | 22.38a | 0.967 | 0.005 |
a,bMeans lacking a common superscript letter within a row differ (P < 0.05).
Abbreviations: DEP, dried egg product; I-143, infected birds receiving 143 U/tonne of DEP; I-287, infected birds receiving 287 U/tonne of DEP; ICON, infected control; UCON, uninfected control.
Only significant results are shown. The UCON group was not included in the statistical analysis owing to lack of variation in the data. All birds in the infected groups received an oral inoculum containing 200,000 sporulated oocysts of E. acervulina.