Table 3.
Multivariate analysis of duration of mechanical ventilation and successful weaning
| Variables | Regression coefficient | 95% confidence interval | t value | P value † |
|---|---|---|---|---|
| Duration of mechanical ventilation | ||||
| Age | −0.80 | −1.31 to −0.28 | −3.09 | <0.01 |
| Female | 5.98 | −10.06 to 22.02 | 0.74 | 0.46 |
| BMI | −0.26 | ‐2.30 to 1.78 | −0.26 | 0.80 |
| Frailty | 17.97 | 1.77 to 34.17 | 2.20 | 0.03 |
| SOFA score | −1.16 | −4.08 to 1.76 | −0.79 | 0.43 |
| Vasopressor use | 16.60 | −9.25 to 42.46 | 1.28 | 0.21 |
| Variables | Hazard ratio | 95% confidence interval | P value ‡ |
|---|---|---|---|
| Successful weaning | |||
| Age | 1.00 | 0.98 to 1.01 | 0.69 |
| Female | 1.00 | 0.58 to 1.71 | 0.99 |
| BMI | 1.01 | 0.94 to 1.07 | 0.89 |
| Frailty | 0.60 | 0.36 to 1.00 | 0.048 |
| SOFA score | 0.97 | 0.89 to 1.06 | 0.50 |
| Vasopressor use | 1.00 | 0.42 to 2.37 | 0.99 |
Multivariate results were adjusted by age, sex, SOFA score, and vasopressor use. The value of missing data was imputed by the multiple regression model using age, sex, and presence/absence of frailty.
BMI, body mass index; SOFA, Sequential Organ Failure Assessment.
†
Multiple regression analysis.
‡
Fine and Gray multivariate regression model. Death before attempting extubation was a competitive event for successful weaning.