Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 17;11:581673. doi: 10.3389/fimmu.2020.581673

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Chen, Li, Li, Su, Xie, Pan, Chen and Liang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Apremilast ameliorated the inflammation of EAU. (A) The typical fundus images of the different administration on the 21st day after immunization. (B) Clinical scores chart of the five groups. (C) The representative histological images of H&E stain on the 21st day after immunization. (D) Histological scores of five groups. (E–P) The frequency and number of CD4+ T-cells, IL-17A-, and IFN-γ-producing cells that infiltrated the retina were measured by flow cytometry on day 21 after immunization. Apremilast blocked the CD4+ T-cells from entering the retina and reduced the frequency and number the of IL-17A-and IFN-γ-producing cells. Data expressed the mean ± SD, **P < 0.01, ***P < 0.001. N = 6.