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. 2020 Nov 17;11:581673. doi: 10.3389/fimmu.2020.581673

Figure 2.

Figure 2

Apremilast inhibited Teff and strengthened Treg in the DLNs. CD4+ T-lymphocyte subtype on day 21 after immunization were compared between the apremilast treatment (15 mg/kg) and vehicle groups by flow cytometry quantitation. (A–I) The frequency and number of IL17A-, IFNγ-, and TNFα-producing cells. (J–L) The proportion and population of CD4+CD25+Foxp3+ T-cells. Data expressed as mean±SD, **P < 0.01, ***P < 0.001, N = 6.