Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 17;11:581673. doi: 10.3389/fimmu.2020.581673

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Chen, Li, Li, Su, Xie, Pan, Chen and Liang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Apremilast attenuated the EAU via the PI3K/AKT/FoxO1 signaling pathway. (A–I) CD4+ T-lymphocytes from the DLNs of the EAU group induced by IRBP_1-20 for 3 days with or without apremilast treatment were analyzed; the proportion and population of pPI3K+, pAKT+, and pFoxO1+. (J–L) The frequency and number of FoxO1+ CD4+ T-cells with or without apremilast treatment. Data expressed as mean±SD, **P < 0.01, ***P < 0.001, N = 6.