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. 2020 Nov 26;13:4609–4620. doi: 10.2147/DMSO.S282926

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© 2020 Thewjitcharoen et al.

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(A) A typical insulin-induced lipohypertrophy in T2DM patient with ultrasound characteristics of thickening heterogeneous echogenicity of subcutaneous fat. (B) Insulin-induced lipoatrophy in a patient with long-standing T2DM with ultrasonographic findings of lipoatrophy revealed a focal area of decreased thickness and increased heterogeneous echogenicity of subcutaneous fat texture. (C) A T1DM patient with suspected insulin-derived localized amyloidosis based on palpable subcutaneous mass at subumbilical region and homogeneous hypoechoic fat interspersed from ultrasound.