Table 3.
MRI Characteristics at ON Presentation: Segmental Enhancement of AVPs During ON Presentation, n of AVPs with Each Enhanced Segment/n of Available AVP Images (%)
| Enhanced Segment | MOG-IgG + ON | AQP4-IgG + ON | p-value |
|---|---|---|---|
| (n = 26 AVPs) | (n = 30 AVPs) | ||
| Orbital optic nerve | 24/26 (92.3) | 23/30 (76.6) | 0.15 |
| Intracanalicular optic nerve | 24/26 (92.3) | 23/30 (76.6) | 0.15 |
| Intracranial optic nerve | 12/26 (46.1) | 13/30 (43.3) | 0.83 |
| Optic chiasm | 5/26 (19.2) | 6/30 (20.0) | 0.90 |
| Optic tract | 0/26 (0.0%) | 1/30 (3.3) | 0.30 |
| Two or more consecutive enhanced segments | 24/26 (92.3) | 22/30 (73.3) | 0.06 |
| Total enhanced segments, mean ± SD, segments | 2.5 ± 1.06 | 2.1 ± 0.98 | 0.22 |
Abbreviations: ON, optic neuritis; MRI, magnetic resonance imaging; AVP, anterior visual pathway; n, number; MOG-IgG +, myelin oligodendrocyte glycoprotein autoantibody-positive; AQP4-IgG +, aquaporin-4 autoantibody-positive.