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Secukinumab did not reduce binge-like ethanol intake in HDID-1 mice. (a) Experimental timeline of secukinumab treatment relative to DID. (b) Ethanol intake (g/kg/2 hours) for Days 1 and 2. (c) Ethanol intake (g/kg/4 hours); a main effect of sex (F(1,55) = 4.25; P = .04), but no effect of drug (F(3,55) = 1.50; P = .22) or drug by sex interaction (F(3,55) = 0.14; P = .94). Data shown collapsed across sex.
