Table 1.
Comparison of the measured outcomes in each group of rats.
| Group |
Measured outcomes |
|||
|---|---|---|---|---|
| W/D | LIS | PaO2, mmHg | AI, % | |
| Sham group, n = 20 | 2.3 ± 0.2 | 10 ± 2 | 99 ± 1 | 33.21 ± 2.17 |
| I/R group, n = 20 | 5.1 ± 0.3a | 21 ± 4a | 91 ± 2a | 51.03 ± 2.61a |
| I/R+Cur group, n = 20 | 3.2 ± 0.2b | 13 ± 2b | 96 ± 2b | 37.71 ± 3.55b |
| I/R+Cur+antagomir-21 group, n = 20 | 4.9 ± 0.3c | 19 ± 4c | 91 ± 3c | 48.03 ± 2.29b |
Data presented as mean ± SD.
aP < 0.05 compared with the sham group; bP < 0.05 compared with the I/R group; cP< 0.05 compared with the I/R+Cur group; one-way analysis of variance and the least significant differences post-hoc test were used to compare the groups.
W/D, wet weight/dry weight; LIS, lung injury score; PaO2, pressure of oxygen in arterial blood; AI, apoptosis index; I/R, ischaemia-reperfusion; Cur, curcumin; antagomir-21, inhibitor of agomir-21.