Table 3.
Group | TNF-α, mg/ml | IL-1β, μg/l |
---|---|---|
Sham group, n = 20 | 1.31 ± 0.02 | 0.22 ± 0.04 |
I/R group, n = 20 | 4.29 ± 0.17a | 0.71 ± 0.03a |
I/R+Cur group, n = 20 | 1.87 ± 0.19b | 0.31 ± 0.05b |
I/R+Cur+antagomir-21 group, n = 20 | 4.03 ± 0.56c | 0.68 ± 0.03c |
Data presented as mean ± SD.
aP < 0.05 compared with the sham group; bP < 0.05 compared with the I/R group; cP < 0.05 compared with the I/R+Cur group; one-way analysis of variance and the least significant differences post-hoc test were used to compare the groups.
I/R, ischaemia-reperfusion; Cur, curcumin; antagomir-21, inhibitor of agomir-21.