Table 3.
Comparison of neonatal outcomes between neonates from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infected mothers and those from non-infected mothers.
| Neonates from infected women (n = 127) | Neonates from non-infected women (n = 364) | P-value | |
|---|---|---|---|
| Birth weight (mean ± SD g) | 3090 (2755, 3376) | 3112 (2779, 3396) | 0.6 |
| Apgar score ≤7 at 1 min | 14 (11 %) | 31 (8.5 %) | 0.5 |
| Apgar score ≤7 at 5 min | 4 (3.1 %) | 12 (3.2 %) | 1 |
| Umbilical venous lactate ≥5 mmol/l | 13 (10.7 %) | 53 (14.5 %) | 0.28 |
| Respiratory distress | 4 (3.1 %) | 16 (4.3 %) | 0.79 |
| Neonatal ICU admission | 3 (2.3 %) | 12 (3.2 %) | 0.76 |
| Neonatology admission | 11 (8.6 %) | 36 (9.8 %) | 0.82 |
| Seizure | 0 (0.0 %) | 2 (0.5 %) | NS |
| Neonatal death | 0 (0.0 %) | 0 (0.0 %) | NS |
| SARS-CoV-2 RT PCR testing | |||
| At birth (n = 108) | 0 (0.0 %) | – | – |
| 24−48 h after birth (n = 29) | 4 (13.8 %) | – | – |
| Complication related to Covid 19 | 0 (0.0 %) | – | – |
| Re hospitalization related to COVID19 | 0 (0.0 %) | – | – |
COVID-19, coronavirus disease 2019; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; ICU, intensive care unit.
Twins (n = 5, non-infected group) were considered as two separate neonates, the model included a robust variance option for twin pregnancies.
No separation of mother –newborn, skin-to-skin and breakfasting allowed. Mothers were delivered protective measures (hand washing, breast cleaning and wearing a mask when breakfasting).