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. 2020 Nov 16;10:580750. doi: 10.3389/fonc.2020.580750

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Copyright © 2020 Curtin, Whitmire, Rickertsen, Mazza, Canoll, Johnston, Mrugala, Swanson and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cysts are more common amongst younger GBM patients. Age-adjusted rate of presentation with cyst among GBM patients using CBTRUS 2011–2015 GBM population as the “standard population”. Age-adjusted rates are given as cystic cases per 10 GBM cases. The resulting “rate” is not intended for prediction of cyst prevalence, but to allow for the comparison of cyst frequency across age groups in a way that normalizes for the frequency of GBM in that age group. Comparing the rates across age groups shows that cystic GBM is most common among 21–34 year-olds and least common among 75–84 year-olds.