Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 11;12:587989. doi: 10.3389/fnagi.2020.587989

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Villar-Vesga, Henao-Restrepo, Voshart, Aguillon, Villegas, Castaño, Arias-Londoño, Zuhorn, Ribovski, Barazzuol, Cardona-Gómez and Posada-Duque.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Differential phenotype of SAD- and FAD-EVs. (A) Heatmap of the percentages of EVs positive for cell markers (CD41, platelets; CD45, leukocytes; CD105, endothelia; CD235a, erythrocytes; AQ4, astrocytes; CD90, neuronal-like; Annexin, phosphatidylserine and DIOC6, mitochondria) from each CNT, FAD and SAD sample. (B) Comparison of the percentages of EVs positive for cell markers in the grouped data in panel (A). (C) Percentages of EVs double-positive for markers (CD45, leukocyte; CD105, endothelium) in CNT, FAD and SAD. (D) Heatmap of the normalized MFI of cell markers (to mean data from CNT individuals). (E) Comparison of the normalized MFI of cell markers for the grouped data in panel (C). Representative data from CNT, n = 6; SAD, n = 6; FAD, n = 6. Data are plotted as means and SEM. One-way ANOVA, Tukey’s multiple comparison test.; * indicates p < 0.05; ** indicates p < 0.01; *** indicates p < 0.001.