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. 2020 Nov 30;61(13):39. doi: 10.1167/iovs.61.13.39

Figure 3.

Figure 3.

Box plot showing median levels of complement activation products and cytokines in aqueous humor of CNV patients and controls. *P < 0.05, Steel–Dwass test. (A) Median levels of C3a were higher in PCV and drusen-associated nAMD than in controls (PCV vs. controls, P = 0.032; drusen-associated nAMD vs. controls, P = 0.010). (B) There were no significant differences in the levels of C4a for each CNV subtype. (C) The levels of C5a were higher in controls than in PNV (P = 0.039). (D) VEGF levels were higher in all CNV subtypes compared to controls (PNV vs. controls, P = 0.016; PCV vs. controls, P = 0.009; drusen-associated nAMD vs. controls, P = 0.043). (E) MCP-1 levels were higher in PCV and drusen-associated nAMD than in controls (PCV vs. controls, P = 0.039; drusen-associated nAMD vs. controls, P = 0.011).