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. 2020 Nov 30;10(11):e041471. doi: 10.1136/bmjopen-2020-041471

Table 2.

Correlation among baseline inflammatory biomarkers and physiological variables measured on the day of admission

IL-1β IL-2R IL-6 IL-8 IL-10 TNF
Age −0.002 0.426 0.356 0.293 0.261 0.361
0.967 <0.001* <0.001* <0.001* <0.001* <0.001*
Time from onset of symptom to hospital admission −0.061 0.222 −0.011 0.038 −0.069 −0.055
0.289 <0.001* 0.843 0.504 0.226 0.336
Albumin 0.177 −0.527 −0.467 −0.319 −0.346 −0.290
0.003* <0.001* <0.001* <0.001* <0.001* <0.001*
ALT −0.047 0.276 0.250 0.198 0.167 0.248
0.415 <0.001* <0.001* 0.001* 0.003* <0.001*
Creatinine −0.037 0.332 0.355 0.226 0.284 0.439
0.512 <0.001* <0.001* <0.001* <0.001* <0.001*
Uric acid 0.033 0.170 0.155 0.128 0.052 0.331
0.578 0.004* 0.054 0.031* 0.387 <0.001*
Total cholesterol −0.021 −0.177 −0.332 −0.080 −0.276 −0.103
0.709 0.002* <0.001* 0.159 <0.001* 0.071
Random blood glucose 0.004 0.303 0.276 0.272 0.336 0.270
0.950 <0.001* <0.001* <0.001* <0.001* <0.001*
D-dimer −0.026 0.614 0.509 0.328 0.378 0.367
0.651 <0.001* <0.001* <0.001* <0.001* <0.001*
Lactic dehydrogenase −0.065 0.598 0.562 0.339 0.472 0.391
0.255 <0.001* <0.001* <0.001* <0.001* <0.001*
CRP 0.008 0.618 0.776 0.345 0.528 0.493
0.894 <0.001* <0.001* <0.001* <0.001* <0.001*
C3 −0.226
0.52
−0.235
0.137
−0.026
0.882
−0.066
0.652
0.093
0.576
−0.262
0.075
C4 0.62
0.053
0.001
0.991
−0.056
0.711
−0.156
0.295
0.070
0.673
−0.21
0.163

Values represent Spearman’s correlation coefficients (upper) and p values (lower).

*Denotes statistically significant correlations.

ALT, alanine aminotransferase; CRP, C reactive protein; IL, interleukin; IL-2R, interleukin 2 receptor; TNF, tumour necrosis factor.