Table 2.
Correlation among baseline inflammatory biomarkers and physiological variables measured on the day of admission
IL-1β | IL-2R | IL-6 | IL-8 | IL-10 | TNF | |
Age | −0.002 | 0.426 | 0.356 | 0.293 | 0.261 | 0.361 |
0.967 | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |
Time from onset of symptom to hospital admission | −0.061 | 0.222 | −0.011 | 0.038 | −0.069 | −0.055 |
0.289 | <0.001* | 0.843 | 0.504 | 0.226 | 0.336 | |
Albumin | 0.177 | −0.527 | −0.467 | −0.319 | −0.346 | −0.290 |
0.003* | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |
ALT | −0.047 | 0.276 | 0.250 | 0.198 | 0.167 | 0.248 |
0.415 | <0.001* | <0.001* | 0.001* | 0.003* | <0.001* | |
Creatinine | −0.037 | 0.332 | 0.355 | 0.226 | 0.284 | 0.439 |
0.512 | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |
Uric acid | 0.033 | 0.170 | 0.155 | 0.128 | 0.052 | 0.331 |
0.578 | 0.004* | 0.054 | 0.031* | 0.387 | <0.001* | |
Total cholesterol | −0.021 | −0.177 | −0.332 | −0.080 | −0.276 | −0.103 |
0.709 | 0.002* | <0.001* | 0.159 | <0.001* | 0.071 | |
Random blood glucose | 0.004 | 0.303 | 0.276 | 0.272 | 0.336 | 0.270 |
0.950 | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |
D-dimer | −0.026 | 0.614 | 0.509 | 0.328 | 0.378 | 0.367 |
0.651 | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |
Lactic dehydrogenase | −0.065 | 0.598 | 0.562 | 0.339 | 0.472 | 0.391 |
0.255 | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |
CRP | 0.008 | 0.618 | 0.776 | 0.345 | 0.528 | 0.493 |
0.894 | <0.001* | <0.001* | <0.001* | <0.001* | <0.001* | |
C3 | −0.226 0.52 |
−0.235 0.137 |
−0.026 0.882 |
−0.066 0.652 |
0.093 0.576 |
−0.262 0.075 |
C4 | 0.62 0.053 |
0.001 0.991 |
−0.056 0.711 |
−0.156 0.295 |
0.070 0.673 |
−0.21 0.163 |
Values represent Spearman’s correlation coefficients (upper) and p values (lower).
*Denotes statistically significant correlations.
ALT, alanine aminotransferase; CRP, C reactive protein; IL, interleukin; IL-2R, interleukin 2 receptor; TNF, tumour necrosis factor.