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. 2020 Dec 1;31(1):17–24. doi: 10.1038/s41422-020-00450-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a hACE2 mice (n = 30) were infected with SARS-CoV-2 (100 μL by intranasally, 1 × 10⁷ TCID₅₀) and their lungs were harvested for viral load analysis at 1, 3, and 5 dpi, respectively (at 5 dpi, both saline and dalbavancin groups had no virus detected). b Histopathology of lungs from saline-treated and dalbavancin-treated mouse groups (5 dpi). c Effects of dalbavancin on body weight of hACE2 mice after SARA-CoV-2 infection. Means ± SD are shown. Statistical significance was measured by two-tail t-test compared with control group. *P < 0.05, **P < 0.01.