Table 3.
Changes in the mean fluorescence intensity of surface multipotent mesenchymal stromal cell antigens during co-cultivation with peripheral blood mononuclear cells expressed as the fold change relative to multipotent mesenchymal stromal cells cultured without peripheral blood mononuclear cells
|
Time of co-cultivation
|
1 d
|
4 d
|
||
|
Group of MSC samples
|
Effective
|
Ineffective
|
Effective
|
Ineffective
|
| HLA-ABC | 1.90 ± 0.11 | 1.53 ± 0.30 | 1.90 ± 0.15 | 1.67 ± 0.33 |
| CD90 | 0.95 ± 0.04 | 0.79 ± 0.061 | 0.55 ± 0.04 | 0.49 ± 0.10 |
| HLA-DR | 134.37 ± 63.90 | 654.74 ± 363.49 | 682.42 ± 326.38 | 151.88 ± 96.44 |
| CD105 | 1.08 ± 0.06 | 0.98 ± 0.14 | 0.64 ± 0.05 | 0.42 ± 0.07 |
| CD146 | 0.82 ± 0.07 | 0.86 ± 0.30 | 22.16 ± 16.28 | 0.81 ± 0.21 |
| CD54 | 60.59 ± 12.29 | 44.76 ± 8.84 | 33.08 ± 5.30 | 23.19 ± 7.64 |
| CD274 | 434.64 ± 93.56 | 1.27 ± 0.281 | 573.44 ± 172.78 | 319.25 ± 233.40 |
| CD73 | 1.05 ± 0.08 | 0.56 ± 0.131 | 150.36 ± 103.94 | 1.60 ± 0.54 |
1
Significant differences between effective and ineffective samples. MSC: Multipotent mesenchymal stromal cell.