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. 2020 Nov 30;5(6):e000990. doi: 10.1136/esmoopen-2020-000990

Table 3.

Comparing relationships between first and second primary uveal melanomas (UM) and the other malignancies

Characteristics First primary UM Second primary UM
Age at diagnosis of the other malignancy (mean age in years, SD) 70.6 (11) 61.8 (11.9)
Independent-samples Mann-Whitney U test
p<0.0001
Latency period between UM and the other malignancy (mean latency in months, SD) 106.7 (88.5) 103.4 (82.6)
Independent-samples Mann-Whitney U test
p=0.95
Site of the other malignancy
 Breast* 65 (24.9) 94 (47.7)
 Prostate* 110 (28.6) 116 (48.3)
 Colon and rectum 61 (9.4) 53 (12.1)
 Lung and bronchus 82 (12.7) 12 (2.7)
 Urinary bladder 36 (5.6) 26 (5.9)
 Melanoma of the skin 61 (9.4) 38 (8.7)
 Corpus uteri* 17 (6.5) 16 (8.1)
 Non-Hodgkin's lymphoma 19 (2.9) 11 (2.5)
 Oral cavity and pharynx 7 (1.1) 10 (2.3)
 Thyroid 11 (1.7) 12 (4.6)
 Ovary* 10 (3.8) 9 (2.1)
 Leukaemia 18 (2.8) 9 (2.1)
 Kidney and renal pelvis 27 (4.2) 7 (1.6)
 Eye and orbit 9 (1.4) 2 (0.5)
 Other sites 113 (17.5) 22 (5)

*Percentages for these cancer were calculated as gender based (the denominator was males/females instead of the overall population).