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Gonadotropin-Releasing Hormone Analogs used in Central Precocious Puberty in the United States
| Formulation | Frequency | Dose | Route |
|---|---|---|---|
| Leuprolide | Monthly 3-monthly |
0.2–0.3 mg/kg every 1 month 11.25 or 30 mg every 3 months |
Intramuscular injection Intramuscular injection |
| 6-monthly | 45 mg every 6 months (89) | Subcutaneous injection | |
| Triptorelin | 6-monthly | 22.5 mg every 6 months | Intramuscular injection |
| Histrelin | 1–2 years | 50 mg every 1–2 years | Subcutaneous implant |
