TABLE 1.
The description of study groups.
| BD group | HC group | P-values | |
| Age [years, mean (SD)]a | 36 (6.4) | 35 (10.2) | 0.420 |
| Sex (men/women)b | 7/11 | 9/9 | 0.411 |
| BD type (I/II) | 9/9 | – | |
| Number of BD patients with history of psychotic symptoms | 5 | – | |
| Duration of treatment [years, mean (SD)] | 6.6 (6.1) | ||
| Number of affective episodes [mean, (SD)] | 9.6 (11.0) | ||
| Number of hypomanic episodes [mean, (SD)] | 1.1 (1.4) | ||
| Number of manic episodes [mean, (SD)] | 2.7 (5.7) | ||
| Number of depressive episodes [mean, (SD)] | 5.8 (6.5) | ||
| Mean head motiona | 0.077 (0.036) | 0.073 (0.039) | 0.756 |
| Medication | |||
| Number of patients (%) | Dose [mean mg (SD)] | ||
| Quetiapine | 6 (32%) | 367.7 (233.8) | |
| Olanzapine | 7 (37%) | 9.6 (4.7) | |
| Valproic acid | 10 (53%) | 980 (315.5) | |
at-test. bChi-square test. BD, bipolar disorder; HC, healthy controls; SD, standard deviation. Head motions in millimeters were evaluated according to the frame-wise displacement criteria by Van Dijk et al. (2012).