Table 2.

Adverse effects.

Parameter	FLOT	SOX
WBC decreased
Grade 0, 1, 2	30 (96.8)	24 (100.0)
Grade 3, 4	1 (3.2)	0
Neutrophil count decreased
Grade 0, 1, 2	29 (93.5)	22 (91.7)
Grade 3, 4	2 (6.5)	2 (8.3)
Febrile neutropenia
Grade 0, 1, 2	31 (100.0)	23 (95.8)
Grade 3, 4	0	1 (4.2)
Anemia
Grade 0, 1, 2	27 (87.1)	22 (91.7)
Grade 3, 4	4 (12.9)	2 (8.3)
Platelet count decreased
Grade 0, 1, 2	30 (96.8)	24 (100.0)
Grade 3, 4	1 (3.2)	0
Aminotrasferase increased
Grade 0, 1, 2	30 (96.8)	24 (100.0)
Grade 3, 4	1 (3.2)	0
Nausea
Grade 0, 1, 2	30 (96.8)	24 (100.0)
Grade 3, 4	1 (3.2)	0
Vomiting
Grade 0, 1, 2	30 (96.8)	24 (100.0)
Grade 3, 4	1 (3.2)	0
Diarrhea
Grade 0, 1, 2	31 (100.0)	24 (100.0)
Grade 3, 4	0	0
Peripheral neuropathy
Grade 0, 1, 2	31 (100.0)	24 (100.0)
Grade 3, 4	0	0
Fatigue
Grade 0, 1, 2	31 (100.0)	24 (100.0)
Grade 3, 4	0	0
Anorexia
Grade 0, 1, 2	30 (96.8)	24 (100.0)
Grade 3, 4	1 (3.2)	0
Oral mucositis
Grade 0, 1, 2	31 (100.0)	24 (100.0)
Grade 3, 4	0	0

Analysis of per-protocol population except otherwise indicated.