Table 3.
Post neoadjuvant chemotherapy (NAC) CT evaluation.
| Parameter | FLOT | SOX | P value |
|---|---|---|---|
| Tumor (post-NAC CT) | |||
| T1 | 1 (3.2) | 1 (4.2) | 0.412 |
| T2 | 9 (29.0) | 10 (41.7) | |
| T3 | 13 (41.9) | 5 (20.8) | |
| T4A | 8 (25.8) | 8 (33.3) | |
| Lymph node (post-NAC CT) | |||
| N0 | 4 (12.9) | 7 (29.2) | 0.214 |
| N1 | 12 (38.7) | 9 (37.5) | |
| N2 | 15 (48.4) | 7 (29.2) | |
| N3 | 0 | 1 (4.2) | |
| TNM stage (post-NAC CT) | |||
| I | 3 (9.7) | 5 (20.8) | 0.435 |
| IIA | 7 (22.6) | 6 (25.0) | |
| IIB | 1 (3.2) | 2 (8.3) | |
| III | 20 (64.5) | 11 (45.8) | |
| Response rate | |||
| PR | 22 (71.0) | 14 (58.3) | 0.691 |
| SD | 8 (25.8) | 9 (37.5) | |
| PD | 1 (3.2) | 1 (4.2) | |
| Overall response rate (ITT population) | 22 (55.0) | 14 (41.2) | 0.254 |
| Disease control rate (ITT population) | 30 (75.0) | 23 (67.6) | 0.606 |
Analysis of per-protocol population except otherwise indicated (the Fisher’s exact test).