Table 3.
Complications Between Drug Resistant and Sensitive Cases of S. Typhi in Karachi, Pakistan, September 2016–September 2019
| S. Typhi (MDR/XDR Cases) | S. Typhi (non MDR/ XDR Cases) | ||||
|---|---|---|---|---|---|
| Complications | n = 1650 | % | n = 443 | % | Pvalue |
| Hepatitis | 20 | 1.2 | 1 | .2 | .1 |
| Hemodynamic shock | 13 | .8 | 0 | 0 | .083 |
| Pulmonary complications | 10 | .6 | 0 | 0 | .13 |
| GI complication | 9 | .6 | 0 | 0 | .22 |
| Intestinal perforation | 8 | .5 | 0 | 0 | .22 |
| Sepsis | 6 | .4 | 0 | 0 | .35 |
| Intestinal obstruction | 6 | .4 | 1 | .2 | 1 |
| Encephalopathy | 3 | .2 | 2 | .5 | .29 |
| Renal impairment | 2 | .1 | 0 | 0 | 1 |
| Blood cell disorders | 2 | .1 | 0 | 0 | 1 |
| Others (myocarditis/wound infection/disseminated intravascular coagulation (DIC) /musculoskeletal complications/electrolyte imbalance) | 4 | .2 | 0 | 0 | .58 |
| At least one or more than one complications iIndividuals) | 58 | 3.5 | 4 | .90 | .005 |
| All Admissionsa | n = 710 mean (SD) |
n = 145 mean (SD) |
|||
| Duration/Days of hospitalization | 9.98 (7.87) | 10.43 (10.61) | .555 | ||
| Temperature at admissionb | 101.45 (1.63) | 101.18 (1.89) | .109 | ||
aAll admissions includes patients recruited at OPD, IPD, Hospital Lab, Surgical.
bTemperature at admission: S. Typhi (MDR/XDR Cases) n = 687/710, information not available n = 23. S. Typhi (non MDR/ XDR Cases) n = 144/145, information not available n = 1.
S. Typhi = 831/855, information not available n = 24.