Table 4.
Characteristics of Patients With Blood Culture–Confirmed Enteric Fever (Salmonella Typhi and Paratyphi A) Enrolled in the Surveillance for Enteric Fever in Asia Project (SEAP) by Outcome 6 Weeks Following Enrollment—Bangladesh, Nepal, and Pakistan, 2016–2019
| Known Outcomea (n = 8089) | Lost to Follow-up (n = 610) | Died (n = 6) | |
|---|---|---|---|
| Demographics | |||
| Age, median (IQR), years | 8 (4–19) | 6 (3–12) | 6 (2–33) |
| Male gender, n (%) | 4622 (57) | 356 (58) | 4 (67) |
| Isolate characteristics | |||
| S. Typhi serovar, n (%) | 7037 (87) | 548 (90) | 6 (100) |
| Fluoroquinolone resistance,b n/N (%) | 7630/7990 (95) | 561/602 (93) | 6 (100) |
| S. Typhi third-generation cephalosporin resistance,b n/N (%) | |||
| Bangladesh | 0/3797 (0) | 0/268 (0) | 0/0 (0) |
| Nepal | 0/1268 (0) | 0/80 (0) | 0/2 (0) |
| Pakistan | 1223/1900 (64) | 136/192 (71) | 4/4 (100) |
| Severity | |||
| Time from fever onset to hospital presentation,c median (IQR), days | 5 (3–7) | 5 (3–7) | 8 (4–14) |
| Prior antibiotic use,d n/N (%) | 3077 (38) | 253 (41) | 3 (50) |
| Hospitalized, n (%) | 2600/8056 (32) | 199/607 (33) | 5 (83) |
| Duration of hospital stay,e median (IQR), days | 5 (3–7) | 6 (3–8) | 7 (5–9) |
| Complications,e n (%) | 81/4732 (1.7) | 8/469 (1.7) | 1 (17) |
N = 8705.
Abbreviation: IQR, interquartile range.
aDoes not include the 6 patients who died.
bPatients with antimicrobial resistance testing results available.
cIncludes patients from SEAP hospitals only (not laboratory network sites).
dPatient or caregiver reported.
eAmong patients with medical charts available for review.