Table 4.
Crude and Adjusted Incidence Rate of Hospitalization of Laboratory-confirmed S. Typhi and S. Paratyphi Among Children Aged <15 by Organism, Sex, Age Group and Recruitment Location, at the Catchment Area of Dhaka Shishu Hospital and Dr MR Khan Shishu Hospital, Dhaka, Bangladesh, July 2017–June 2019
Characteristics | Number of hospitalized cases | Population | Crude incidence rate per 100 000/year (95% CI) | Febrile cases hospitalized at study hospitals | Health-care seeking adjusted incidence per 100 000/year (95% CI) | Facility captured febrile cases at study hospitals | Facility capture adjusted incidence per 100 000/year (95% CI) | Blood culture sensitivity | Blood culture sensitivity adjusted incidence per 100 000/year (95% CI) |
---|---|---|---|---|---|---|---|---|---|
Overall enteric fever | 523 | 1 148 076 | 46 (42–49) | 53% | 86 (81–92) | 47% | 185 (177–193) | 61% | 303 (293–313) |
Organism | |||||||||
S. Typhi | 478 | 1 148 076 | 42 (38–45) | 53% | 79 (74–84) | 47% | 169 (161–177) | 61% | 277 (267–287) |
S. Paratyphi A | 45 | 1 148 076 | 3.9 (2.8–5.1) | 53% | 7.4 (5.8–9) | 4% | 16 (14–18) | 61% | 26 (23–29) |
Sex | |||||||||
Male | 276 | 584 730 | 47 (42–53) | 54% | 88 (80–95) | 47% | 185 (174–196) | 61% | 303 (289–317) |
Female | 247 | 563 346 | 44 (38–49) | 51% | 86 (78–93) | 46% | 188 (176–199) | 61% | 308 (293–322) |
Age | |||||||||
<2 years | 70 | 155 915 | 45 (34–55) | 58% | 78 (64–92) | 40% | 193 (171–215) | 61% | 316 (288–344) |
2 to <5 years | 209 | 225 453 | 93 (80–105) | 57% | 163 (146–179) | 48% | 337 (313–361) | 61% | 552 (522–583) |
5 to <15 years | 244 | 766 708 | 32 (28–36) | 46% | 69 (63–75) | 50% | 138 (129–146) | 61% | 225 (215–236) |
6 months to <15 years | 522 | 1 110 388 | 47 (43–51) | 51% | 91 (86–97) | 47% | 195 (187–203) | 61% | 319 (309–330) |
Enrollment location | |||||||||
OPD | 106 | 1 148 076 | 9.2 (7.5–11) | 53% | 17 (15–20) | 44% | 40 (36–43) | 61% | 65 (60–70) |
IPD | 368 | 1 148 076 | 32 (29–35) | 53% | 61 (56–65) | 84% | 72 (67–77) | 61% | 118 (112–125) |
Hospital lab | 49 | 1 148 076 | 4.3 (3.1–5.5) | 53% | 8.1 (6.4–10) | 100% | 8.1 (6.4–10) | 61% | 13 (11–15) |
Abbreviations: CI, confidence interval; IPD, inpatient department; OPD, outpatient department; S., Salmonella.