Table 4.
Comparison of Salmonella enterica serovar Typhi and S. enterica serovar Paratyphi A among patients with culture-confirmed enteric fever — Bangladesh, Nepal, and Pakistan, 2016–2019
| S. Tyhpi, n = 4610 | S. Paratyhpi A, n = 605 | P value | |
|---|---|---|---|
| Age in years | 11.5 (5.6–17.4) | 13.5 (7.7–19.4) | <.001 |
| Female | 43.3% (41.1–45.5) | 42.1% (37.9–46.4) | .582 |
| Inpatient | 20.8% (11.0–35.8) | 12.7% (6.2–24.1) | <.001 |
| Fever duration in daysa | 7.6 (6.3–8.8) | 6.9 (5.7–8.2) | .002 |
| Temperature at presentation, °Fa | 100.8 (100.5–101.1) | 100.2 (99.8–100.5) | <.001 |
| Febrile at presentation/admission, >99.5°Fa | 70.4% (64.6–75.6) | 61.6% (53.9–68.8) | <.001 |
| High-grade fever at presentation/admission, ≥103°Fa | 15.1% (10.0–22.1) | 8.7% (5.2–14.0) | <.001 |
| Days of being unable to conduct activitya | 4.6 (2.6–6.6) | 4.0 (2.0–6.0) | <.001 |
| Antibiotics taken prior to presentation/admission | 54.1% (44.6–63.3) | 47.2% (37.2–57.4) | .002 |
| Cougha | 31.3% (23.0–41.1) | 32.9% (23.6–43.7) | .497 |
| Diarrheaa | 25.6% (18.5–34.4) | 17.4% (11.6–25.2) | <.001 |
| Constipationa | 4.6% (2.6–7.9) | 3.0% (1.5–6.0) | .064 |
| Abdominal paina | 35.8% (22.6–51.6) | 30.7% (18.4–46.6) | .036 |
| Vomitinga | 41.8% (30.8–53.6) | 31.5% (21.6–43.4) | <.001 |
| Nauseaa | .6% (.2–1.5) | 1.4% (.5–4.3) | .003 |
| Headachea | 32.5% (12.3–62.3) | 33.2% (12.4–63.6) | .836 |
| Leukopeniaa | 10.5% (5.9–17.8) | 8.3% (4.1–15.8) | .254 |
| Thrombocytopeniaa | 13.9% (7.3–25.0) | 8.3% (3.8–17.1) | .009 |
Data are among patients with culture-confirmed enteric fever in Bangladesh, Nepal, and Pakistan.
aAdjusted for age.