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. 2020 Nov 4;120(22):12357–12489. doi: 10.1021/acs.chemrev.0c00451

Table 10. Overview of Nanosensors Based on Carbonaceous Materials.

material preparation method comment ref
carbon dots various a review on CDs for use in pH sensing (851)
hydrothermal method from Agaricus bisporus in microgels to monitor 3D cell culture scaffolds (820830)
from polyethylenimine pH range 2–12, cellular uptake (819)
from flower (carnation) pH range 3–12, absorptiometric and fluorometric (821)
from chloroform and diethylamine coupled to fluorescein, CD as reference (822)
hydrothermal method from β-resorcylic acid and ethylenediamine linear pH range 3.8–6.2 (852)
nitrogen- and chloride-doped CD from urea in choline chloride–glycerine deep eutectic solvent pH range 5–10, virtually no effect of ionic strength (823)
hydrothermal method from mushrooms pH range 2–13, linear range 4–8, quenched by hemin (824)
hydrothermal method from ascorbic acid intensity decrease 10-fold (pH 4–8) emission shift from 441 to 550 nm (pH 2–12) (853)
thermal decomposition of ascorbic acid in DMSO in microfluidic system absorptiometric, fluorometric, upconversion (825)
hydrothermal method from p-phenylenediamine excitation-independent emission at 590 nm (826)
from glucose and edible oil linear range pH 3–13 (827)
hydrothermal method from citric acid and dicyandiamide or aniline hydrochloride high quantum yields 37% (854)
63% (855)
hydrothermal method from citric acid and basic fuchsin dual emission with different pH-dependent behavior allowing ratiometric measurement (856)
hydrothermal method from citric acid and l-serine or monoethanolamine linear range pH 1.5–7.5 (857)
from phenylenediamine emission peaking at 620 nm under 470 nm excitation; 15% quantum yield; 3.8 nm i.d.; used to image pH values in E. coli bacteria, pH 5–10 (858)
CDs doped with Eu(III), Tb(III) and a chelating ligand from PEG 400 excitation/emission wavelengths of 272/545 (Tb) and 272/614 nm (Eu); effects are due to pH-induced variations in energy transfer; applied to visualize pH values in breast adenocarcinoma, pH 3–10 (859)
nitrogen and oxygen-rich CD from aspartic acid and urea pH range 1–13, sensitive toward oxidation (860)
hydrothermal method from o-phenylenediamine PEG, oxalic acid dual emission, ratiometric, linear range pH 2.2–4.0 (861)
nitrogen- and boron-doped CD from aminophenylboronic acid dual emission with different pH-dependent behavior allowing ratiometric measurement (862)
CD Eu(III) doped hydrothermal method from EDTA and (Eu(NO3)3*6H2O) ratiometric response to pH from pH 2–10 (863)
N- and P-doped CD CD treated with diammonium phosphate dual emission with different pH-dependent behavior allowing ratiometric measurement, linear range 2–12 (864)
B- and P-doped CD CD treated with H3BO3 or phosphoric acid boron doping increased QY, phosphorus doping decreased QY, ratiometric (865)
CD with polyaniline layer two linear regions from pH 3.5–5.5 and 6–12 (866)
nitrogen-rich carbon NPs hydrothermal method from melamine and triethanolamine PET quenching, linear range 3–12 (867)
CD with fluorescein from acrylic acid and 1,2-ethanediamine FRET-based, ratiometric (834835)
CD with fluorescein and rhodamine B from citric acid and 4,7,10-trioxa-1,13-tridecanediamine ratiometric pH 6–8 (836)
CD with fluorescein from kelp juice CD as reference, linear range 4.6–7.7 (831)
GO nanosheets   10-fold fluorescence quenching on going from pH 2 to 12, show strong cross-talk to ionic strength (849)
  pH sensitivity from carboxylic and phenolic groups (98)
betaine-modified pH range 4–12, quenched by Cu2+ and Fe3+ (868)
GO NPs   bathochromic shift of emission in pH range 1 to 14, strong temperature sensitivity (869)
  transducer for urea detection (870)
single-walled carbon nanotubes   in wavelength range from 1.1–1.4 μm, pH range 4.5–8.5, temperature sensitive (850)