Table 2.
sPD‐L1 < 90 | sPD‐L1 ≥ 90 | |||
---|---|---|---|---|
Response | N = 233 | (N = 192) | (N = 41) | P‐value |
Complete response | 0 | 0 | 0 | |
Partial response | 56 (24%) | 47 (24%) | 9 (22%) | |
Stable disease | 69 (30%) | 63 (32%) | 6 (15%) | |
Progressive disease | 100 (43%) | 78 (40%) | 22 (54%) | |
Not evaluable | 8 (3%) | 4 (2%) | 4 (10%) | |
ORR% (95% CI) | 24% (19%–30%) | 24% (11%–38%) | 22% (19%–31%) | 0.731 |
DCR% (95% CI) | 54% (47%–60%) | 57% (50%–64%) | 37% (22%–53%) | 0.0158 |
The disease control rate was defined as the percentage of patients with a complete or partial response or stable disease.
DCR, disease control rate; ORR, objective response rate; sPD‐L1, soluble programmed death ligand 1.