Table 3.

Diagnostic performance and unforeseen N2 disease in patients after mediastinal staging divided into different groups

	Overall	Group 1 (N = 210)	Group 2 (N = 78)	Group 3 (N = 24)
Diagnostic performance:
Total mediastinal staging:
Sensitivity	94%	99%	71%	75%
Negative predictive value	91%	97%	92%	75%
Endosonography:
Sensitivity	88%	95%	33%	80%
Negative predictive value	80%	83%	84%	80%
Mediastinoscopy:
Sensitivity	74%	100%	74%	25%
Negative predictive value	91%	100%	88%	63%
Unforeseen N2 disease:
During mediastinoscopy after negative endosonography (N = 50)	22%	20.1%	35.7%	0%
During surgery after negative staging (N = 112)	8.9%
During direct surgery (N = 222)	2.7%	2.5%	7.8%	25%