Table 1.

Impact of the stay-at-home order on stroke admission and metrics during the COVID-19 pandemic

	Control period (24 March to 23 April 2019)	During stay-at-home order (24 March to 23 April 2020)	p value
Mean age, years	72.4	65.6	0.024
Sex			0.253
Male	41/80 (51.3%)	29/47 (61.7%)
Female	39/80 (48.8%)	18/47 (38.3%)
Race
Caucasian	74/80 (92.5%)	41/47 (87.2%)	0.399
African-American	4/80 (5%)	3/47 (6.4%)
Hispanic	2/80 (2.5%)	2/47 (4.3%)
Others	0/80	1/47 (2.1%)
Stroke risk factors
Hypertension	51/80 (63.8%)	35/47 (74.5%)	0.212
Diabetes mellitus	17/80 (21.3%)	11/47 (29.8%)	0.280
Atrial fibrillation	18/80 (22.5%)	12/47 (29.8%)	0.698
Smoking history	17/80 (21.3%)	11/47 (23.4%)	0.777
Low-density lipoprotein notable	37/80 (46.3%)	25/47 (53.2%)	0.450
A history of prior stroke	23/80 (28.8%)	12/47 (25.5%)	0.695
Stroke subtype
Ischemic stroke	66/80 (82.5%)	37/47 (78.7%)	0.6
Hemorrhagic stroke	12/80 (15.0%)	9/47 (19.2%)	0.050
Subdural hematoma	2/80 (2.5%)	1/47 (2.1%)	0.629
Subarachnoid hemorrhagia	0/80	0/47
Initial NIHSS score			0.261
0–4	37/66 (56.1%)	15/36 (41.7%)
5–15	19/66 (28.8%)	13/36 (36.1%)
16–20	3/66 (4.6%)	5/36 (13.9%)
21–42	7/66 (10.6%)	3/36 (8.3%)
Difference in LKW and ED time			0.008
<4.5 h	19/58 (32.8%)	19/36 (52.8%)
4.5–12 h	11/58 (19.0%)	2/36 (5.6%)
12–24 h	9/58 (15.5%)	11/36 (30.6%)
>24 h	19/58 (32.8%)	4/36 (11.1%)
Administration of tPA	13/80 (16.3%)	14/47 (29.8%)	0.072
tPA time			0.183
<90 mins	0/13 (0%)	4/14 (28.6%)
91–180 mins	9/13 (69.2%)	7/14 (50%)
181–270 mins	4/13 (30.8%)	3/14 (21.4)
Large vessel occlusion	14/80 (17.5%)	16/47 (34.8%)	0.028
Mechanical thrombectomy	4/80 (5%)	14/47 (29.8%)	<0.001

Values express n, unless otherwise indicated. COVID-19, 2019-novel Coronavirus; NIHSS, National Institutes of Health Stroke Scale; LKW, last known well; ED, emergency department; tPA, tissue plasminogen activator.