Supplementary Table 9.

Cellular components identified by gene set enrichment analysis in A–F1 versus N–F1 contrast

Cellular components	NES	FDR
Centrosome	−2.71	0.00
Motile cilium	−2.61	0.00
Cilium	−2.59	0.00
Microtubule organizing center part	−2.58	0.00
Ciliary basal body	−2.56	0.00
Nuclear pore	−2.56	0.00
Centriole	−2.54	0.00
Ciliary part	−2.54	0.00
Kinesin complex	−2.52	0.00
Ciliary plasm	−2.50	0.00
Microtubule-associated complex	−2.47	0.00
Sperm part	−2.37	0.00
Intraciliary transport particle	−2.36	0.00
Kinetochore	−2.35	0.00
Dynein complex	−2.34	0.00
Ciliary tip	−2.33	0.00
Spindle	−2.28	0.00
Axoneme part	−2.25	0.00
Microtubule	−2.24	0.00
Chromosome centromeric region	−2.23	0.00
Sperm flagellum	−2.22	0.00
Condensed chromosome centromeric region	−2.21	0.00
Condensed chromosome	−2.19	0.00
Spindle pole	−2.13	0.00
Pericentriolar material	−2.12	0.00
Intraciliary transport particle B	−2.10	0.00
Inclusion body	−2.09	0.00
Nuclear envelope	−2.07	0.00
Chromosomal region	−2.05	0.00
Acrosomal vesicle	−2.04	0.00
DNA repair complex	−2.04	0.00
Acetyltransferase complex	−2.02	0.00
DNA-directed RNA polymerase II holoenzyme	−2.01	0.00
Sperm’s principal piece	−2.01	0.00
Ribonucleoprotein granule	−2.00	0.00
PML body	−2.00	0.00

The 36 cellular components showed in this table were selected on the basis of NES ≥2.0 and FDR <0.05. The molecular signature database (v6.2) searched was cellular components using GSEA approach (http://www.broadinstitute.org/gsea). The ten cellular components in bold text were included in the leading-edge analysis. NES: normalized enrichment score; FDR: false discovery rate; GSEA: gene set enrichment analysis