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. 2020 May 26;11(1):134–146. doi: 10.1515/tnsci-2020-0103

Table 4.

ROC analysis of all variables in all groups

Parameter Group Area under the curve Cutoff value Sensitivity (%) Specificity (%) p value
Lipid peroxides PPA 0.990 0.515 100.0 85.7 0.002
PPA + Novavit 0.959 0.515 85.7 85.7 0.004
Ascorbic acid PPA 0.837 24.865 85.7 85.7 0.035
PPA + Novavit 0.673 24.605 57.1 85.7 0.277
Glutathione PPA 1.000 82.290 100.0 100.0 0.002
PPA + Novavit 0.796 93.192 100.0 71.4 0.064
PLA2 PPA 0.755 1527.55 85.7 85.7 0.110
PPA + Novavit 0.735 1507.70 85.7 85.7 0.142
ALOX5 PPA 1.000 385.89 100.0 100.0 0.002
PPA + Novavit 0.918 275.305 100.0 71.4 0.009
COX2 PPA 1.000 73.29 100.0 100.0 0.002
PPA + Novavit 0.633 71.58 57.1 100.0 0.406
Phospholipid assay (mM/g brain tissue) PPA 0.878 15.56 85.7 71.4 0.018
PPA + Novavit 0.878 15.10 85.7 71.4 0.018
Leukotriene B4 (pg/g brain tissue) PPA 0.796 397.435 85.7 85.7 0.064
PPA + Novavit 0.959 396.854 100.0 85.7 0.004
PGE2 (pg/g brain tissue) PPA 0.684 244.765 71.4 71.4 0.250
PPA + Novavit 0.673 243.030 57.1 85.7 0.277