Table 4.
Parameter | Group | Area under the curve | Cutoff value | Sensitivity (%) | Specificity (%) | p value |
---|---|---|---|---|---|---|
Lipid peroxides | PPA | 0.990 | 0.515 | 100.0 | 85.7 | 0.002 |
PPA + Novavit | 0.959 | 0.515 | 85.7 | 85.7 | 0.004 | |
Ascorbic acid | PPA | 0.837 | 24.865 | 85.7 | 85.7 | 0.035 |
PPA + Novavit | 0.673 | 24.605 | 57.1 | 85.7 | 0.277 | |
Glutathione | PPA | 1.000 | 82.290 | 100.0 | 100.0 | 0.002 |
PPA + Novavit | 0.796 | 93.192 | 100.0 | 71.4 | 0.064 | |
PLA2 | PPA | 0.755 | 1527.55 | 85.7 | 85.7 | 0.110 |
PPA + Novavit | 0.735 | 1507.70 | 85.7 | 85.7 | 0.142 | |
ALOX5 | PPA | 1.000 | 385.89 | 100.0 | 100.0 | 0.002 |
PPA + Novavit | 0.918 | 275.305 | 100.0 | 71.4 | 0.009 | |
COX2 | PPA | 1.000 | 73.29 | 100.0 | 100.0 | 0.002 |
PPA + Novavit | 0.633 | 71.58 | 57.1 | 100.0 | 0.406 | |
Phospholipid assay (mM/g brain tissue) | PPA | 0.878 | 15.56 | 85.7 | 71.4 | 0.018 |
PPA + Novavit | 0.878 | 15.10 | 85.7 | 71.4 | 0.018 | |
Leukotriene B4 (pg/g brain tissue) | PPA | 0.796 | 397.435 | 85.7 | 85.7 | 0.064 |
PPA + Novavit | 0.959 | 396.854 | 100.0 | 85.7 | 0.004 | |
PGE2 (pg/g brain tissue) | PPA | 0.684 | 244.765 | 71.4 | 71.4 | 0.250 |
PPA + Novavit | 0.673 | 243.030 | 57.1 | 85.7 | 0.277 |