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. 2020 Nov 12;23(1):48. doi: 10.3892/mmr.2020.11686

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Copyright: © Lu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Establishment of osimertinib-resistant non-small cell lung cancer cells. (A) Effects of osimertinib on cell viability were analyzed using an MTT assay in HCC827 and HCC-827/OR cells. (B) Representative profiles of apoptosis induced by osimertinib and (C) quantitative results were obtained using PE/FITC staining in HCC827 cells. (D) Representative profiles of apoptosis induced by osimertinib and (E) quantitative results were obtained using PE/FITC staining in HCC827/OR cells. Data are presented as the mean ± SD from three independent experiments. *P<0.05 vs. DMSO treatment group.