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. 2020 Nov 16;63(22):13719–13732. doi: 10.1021/acs.jmedchem.0c01277

Scheme 2. Different Possible Isomers of COTI-2. The Z- and E′-Isomers Have Strongly Downfield Shifted NH Rresonance NMR Signals due to the Presence of Intramolecular Hydrogen Bonds.

Scheme 2