Table 1.
Transcripts differentially expressed between wild-type and SbIII-resistant L. infantum lines and Gene Ontology (GO) functional enrichment analysis
| GO category: biological process | GO category: cellular component or molecular function | Without GO | Total | ||
|---|---|---|---|---|---|
| Enriched | Not enriched | ||||
| Functional annotationa | |||||
| Upregulated | 111 (11.90%) | 13 (1.39%) | 289 (31.94%) | 18 (1.93%) | 431 (46.19%) |
| Downregulated | 37 (3.96%) | 0 | 6 (0.64%) | 30 (3.21%) | 73 (7.82%) |
| Hypothetical proteinsb | |||||
| Upregulated | 32 (3.43%) | 13 (1.39%) | 142 (15.22%) | 219 (23.47%) | 406 (43.51%) |
| Downregulated | 1 (0.11%) | 0 | 0 | 22 (2.36%) | 23 (2.79%) |
| Total number of DE transcripts identified | 181 | 26 | 437 | 289 | 933 |
aTranscripts with functional annotation
bTranscripts with no assigned function