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. 2020 Oct 29;6(11):2031–2045. doi: 10.1021/acscentsci.0c00755

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© 2020 American Chemical Society

This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.

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Biocompatibility and hemocompatibility of coatings: (A) Antithrombogenic effect of coatings measured by platelet activation and amount thrombus formation. (B) SEM images of thrombus formed on catheters (Left: before incubation with rabbit whole blood. Right: after 2 h incubation with rabbit whole blood) (i) (#1) unmodified catheter, (ii) (#10) H(N)-b-S (scale bar = 10 μm). (C) Activation of blood immune cells. Student’s t test of #10 against blood w/o treatment, n.s. P > 0.05. (D) Blood protein fouling on catheters after 24 h incubation with protein or serum. Student’s t test of #10 against unmodified catheter, ****P < 0.0001, **P < 0.01.